Toyocerin® has shown many beneficial effects when administered to poultry. It is well known that many factors stress these animals during growth, resulting in an imbalance in the microflora, which in turn opens up the possibility of infection by opportunistic pathogens. In this sense, the administration of Toyocerin® increases the lactobacilli:enterobacteria ratio through its direct effect of inhibiting the growth of gram-negative bacteria (E. coli and Salmonella), as well as Clostridia, which is also indirectly inhibited. In addition, an increased surface area for uptake and an increased number of goblet cells were observed. Even the response to commercial vaccines (IB, IBV, Newcastle) is higher in chickens and layers, demonstrating its ability to boost the immune system.
Toyocerin® can be used in piglets, sows, growing pigs and fattening pigs, according to country registrations. The use of Toyocerin® in these categories has shown numerous effects on the gastrointestinal health, immune system, general health and productivity of the animals. For example, numerous studies show a significant reduction in certain potentially pathogenic bacteria, such as E. coli and Salmonella, and an increase in lactic acid bacteria. In addition, earlier immune development in the piglet and a better response to vaccination have been observed. In sows, improved gut health is reflected in improved performance, with an increase in the number of piglets born and weaned, a reduction in non-productive days and weight loss, improved milk quality and increased immunoglobulins in colostrum.
The efficacy of Toyocerin® in fattening cattle has been demonstrated by Rubinum S.A. in numerous studies. Its use results in an optimal gastrointestinal microbiota and immune response, leading to improved animal productivity. A change in the production of volatile fatty acids in the rumen and intestine and an increase in the absorptive surface of the small intestine are effects observed after administration of Toyocerin® to ruminants.
Toyocerin® can be used in breeding and fattening rabbits. Its main effects are related to the stabilization of the intestinal microflora, which improves the general health of the animal. In this respect, a clear effect of Toyocerin® against Clostridia has been demonstrated.
Toyocerin® also improves the performance in rabbits, with some of the most common examples being an increase in the number of offspring with a higher live body weight per female and a reduction in mortality during fattening. It should also be noted that Toyocerin® is compatible with several coccidiostats approved for use in rabbits.
Toyocerin® has shown beneficial effects when administered to various aquatic species, improving growth, survival and uniformity among the animals. Tests on eel, trout, shrimp and amberjack have demonstrated these results. However, the mode of action is not fully understood, although a positive effect on the organisation of the intestinal mucosa and an improvement in nutrient absorption may be behind the optimisation of production yields and animal health.